Odontobuthus odontrous is one of the medically important and dangerous scorpions belonging to family Buthidae. Present study was aimed to evaluate the presence of low molecular weight peptides in the venom of the O. odontrous. Low molecular weight peptides are therapeutically important and they have significant role in ion channel blocking and tumor growth impairing. For this purpose High Performance Liquid Chromatography was performed. The results of present study confirmed the presence of at least five low molecular weight peptides in the range of 2-8kDa.The recognition of these low molecular weight peptides can not only be an important step in producing effective antivenom against such dangerous scorpion species, but also these peptides are probes for identifying specific types of ion channels. These peptides can also be the important tools for understanding ion channel physiology. Moreover, this study can be helpful in more advancement in drug development, cancer treatment, or other pharmaceuticals.
A large number of interactive queries are being executed day by day. The user expects for an answer without no time after the execution. Even in scientific executions the user needs the intial query results for analysis without waiting for the entire process to complete. The state-of-art join algorithms are not ideal for this settings as most of the algorithms are hash/sort based algorithms, which requires some pre-work before it can produce the results. We propose a new join algorithm, Maximized Result Rate Join Algorithm (MRR), which produces the first few results without much delay. It also produces the maximum join query results during the early stage of the join operation; this is achieved by exploiting the histogram, which is available in database statistics. Histogram provides the frequency of the attribute in a table. The tuples which have high frequency of occurances are joined during the early stages of the join operation. Further using the histogram, the join operation can be terminated when the required matching tuples are obtained. This improves the overall join performance. Experiment results shows that the new MRR join algorithm produces 60% more resultant tuples than the hash and sort-merge join algorithms. It also produces the result 30%-35% early than the traditional join algorithms.
The paper is focused on the identification of Marketing Intelligence techniques implemented in order to achieve a superior positioning on the eco-label food products niche market. The research is performed on a sample of Romanian retailers of eco-label food products. The empirical study analyzes the main sources of gathering data about their competitors, the reasons for monitoring the strategic options of their competitors, the specific instruments of Marketing Intelligence used within the framework of differentiation strategies as well as the results of the relationship marketing policies application with a view to improving their performances. The research outlines several positioning opportunities based on a relevant dataset which can be used with the view of making the target consumers aware of the added-value of these products as concerns a healthier nutrition.
We present the case of a 30 years old patient (male) victim of a high speed car crush assisted by ED Craiova. Coma, severe head trauma, serious chest trauma with multiple rib fractures, bilateral lung contusions, pericardial fluid, multiple spine and pelvic unstable fracture, medullar injury, progressive shock, paroxysmal cardiac dysrhythmias. Increased levels of CKMB with atipical evolution for a myocardial contusion. Two cardiopulmonary arrest (asystole), both resuscitated.\nTaking into account the kinematics and severity of thoracic trauma, myocardial contusion was the first diagnostic hypotheses, but it was also considered the possibility of an acute coronary syndrome, toxicologic ethyology and the spinal cord damage as causes of cardiogenic shock and cardiac rhythm disturbance. \nThe association of neurotrauma, haemorrhage and pulmonary contusion limited treatment of an potential acute coronary syndrome, fast volume replacement and the possibilitys to assist ventilation, in context of shock and risk of secondary brain and spinal injury.\nSpecifying these contingencies determined the management orientation for both possible primary reperfusion and advanced management for neurotrauma.
ABSTRACT\nThe present work is included within a large and complex research project regarding Romanian Grey Steppe breed, unique as biologic and cultural–historic importance, in verge of extinction and involved into a preservation programme of Romanian’s genetic fund. The study of proteic fractions genetic polymorphism, especially of kappa-casein and genotype relations of these lactoproteins with some qualitative and quantitative features of milk production, it is an actual theme and for these breed it is a novelty. Research were carried out on a number of 30 Romanian Grey Steppe cows and focused on: milk production indicators by successive lactations, genetic structure, genetic parameters for some features and serum proteins of milk production. In the first lactation 62.69 % of the maximum lactation was attained, a value which highlights the tardiness of Romanian Grey Steppe breeds in terms of milk production. The milk quantity ranged between 1589.64 kg (1st lactation) and 2535.43 kg in the 5th lactation which was the maximum one. Starting with the 6th lactation, the milk quantity decreased reaching in the 8th lactation the value of 1078.5 kg. Milk fat percentage reached the maximal value in the 5th lactation, namely 4.73 %. The same evolution could be noticed for the percentage of protein which registered the value of 3.71 % in the 5th lactation. The main lactoprotein from milk, kappa-casein (K-cz), characterized in literature as a feature with a high degree of hereditary transmission, in the nucleus under study it acted as such, and its value was confirmed by the heritability index (h2=0.57 %). We must mention the medium values for milk and fat quantities (h2=0.27, 0.30 %) and the fat percentage from milk which had a greater hereditary influence h2 = 0.71 %. Correlations between kappa-casein and milk quantity are negative and powerful. Between kappa-casein and other qualitative features of milk (with fat content 0.58-0.67 % and protein content 0.77-0.87%), there are positive and very powerful correlations.